Identification of MERS-CoV in dromedary camels

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Authors reply: Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels: are dromedary camels a reservoir for MERS-CoV?

In fact, we mentioned in our paper [2] in detail that the cycle threshold (Ct) values in nasal and conjunctival swabs of the five MERS-CoV reverse transcriptionquantitative polymerase chain reaction (RT-qPCR) positive Omani camels ranged from as low as 15.74 to 36.29, indicating a high viral load in the former. Our results were confirmed in a recent report by Raj et al. [3], who demonstrated an...

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Letter to the Editor: Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels: are dromedary camels a reservoir for MERS-CoV?

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MERS Coronaviruses in Dromedary Camels, Egypt

We identified the near-full-genome sequence (29,908 nt, >99%) of Middle East respiratory syndrome coronavirus (MERS-CoV) from a nasal swab specimen from a dromedary camel in Egypt. We found that viruses genetically very similar to human MERS-CoV are infecting dromedaries beyond the Arabian Peninsula, where human MERS-CoV infections have not yet been detected.

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In 2012, a novel coronavirus associated with severe respiratory disease in humans emerged in the Middle East. Epidemiologic investigations identified dromedary camels as the likely source of zoonotic transmission of Middle East respiratory syndrome coronavirus (MERS-CoV). Here we provide experimental support for camels as a reservoir for MERS-CoV. We inoculated 3 adult camels with a human isola...

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Knowledge about immunity to Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels is essential for infection control and vaccination. A longitudinal study of 11 dam-calf pairs showed that calves lose maternal MERS-CoV antibodies 5-6 months postparturition and are left susceptible to infection, indicating a short window of opportunity for vaccination.

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ژورنال

عنوان ژورنال: The Lancet Infectious Diseases

سال: 2014

ISSN: 1473-3099

DOI: 10.1016/s1473-3099(13)70691-1